{"id":5245,"date":"2021-07-11T01:15:12","date_gmt":"2021-07-11T05:15:12","guid":{"rendered":"http:\/\/www.phytonutriment.ca\/?p=5245"},"modified":"2023-03-16T22:10:54","modified_gmt":"2023-03-17T02:10:54","slug":"monographie-sante-canada-rhodiola-roseola","status":"publish","type":"post","link":"https:\/\/www.phytonutriment.ca\/fr\/monographie-sante-canada-rhodiola-roseola\/","title":{"rendered":"Rhodiola roseola &#8211; Monographie Sant\u00e9 Canada"},"content":{"rendered":"<h2><strong>SOURCE- SANT\u00c9 CANADA\u00a0: Nomenclature du compendium des ingr\u00e9dients m\u00e9dicinaux<\/strong><\/h2>\n<h2><strong>M\u00e9dicaments et produits de sant\u00e9 naturels<\/strong><\/h2>\n<h2><strong>Monographie: Rhodiola roseola<\/strong><\/h2>\n<p style=\"text-align: justify;\">La pr\u00e9sente monographie vise \u00e0 servir de guide \u00e0 l&rsquo;industrie pour la pr\u00e9paration de demandes de licence (DLMM) et d&rsquo;\u00e9tiquettes dans le but d&rsquo;obtenir une autorisation de mise en march\u00e9 d&rsquo;un produit de sant\u00e9 naturel. Elle ne vise pas \u00e0 \u00eatre une \u00e9tude approfondie de l&rsquo;ingr\u00e9dient m\u00e9dicinal.<\/p>\n<p><strong>Nota<\/strong><\/p>\n<ul>\n<li style=\"text-align: justify;\">Les parenth\u00e8ses contiennent des \u00e9l\u00e9ments d&rsquo;information facultatifs; il n&rsquo;est pas n\u00e9cessaire de les inclure dans la\u00a0DLMM\u00a0ou sur l&rsquo;\u00e9tiquette du produit.<\/li>\n<li>La barre oblique (\/) indique que les termes ou les \u00e9nonc\u00e9s sont synonymes. \u00a0Le demandeur peut utiliser n&rsquo;importe lequel des termes ou \u00e9nonc\u00e9s indiqu\u00e9s.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>Date<\/strong><\/p>\n<p>24 octobre 2013<\/p>\n<p><strong>Proper name(s)<\/strong><\/p>\n<p><em>Rhodiola rosea<\/em>\u00a0L. (crassulac\u00e9es) (USDA 2007; McGuffin et al. 2000)<br \/>\n(Synonyme :\u00a0<em>Sedum rosea<\/em>\u00a0(L.) Scop. (USDA 2007; McGuffin et al. 2000)))<\/p>\n<p><strong>Nom(s) commun(s)<\/strong><\/p>\n<ul>\n<li>Rhodiole (McGuffin et al. 2000)<\/li>\n<li>Orpin rose (passeportsant\u00e9 2011)<\/li>\n<\/ul>\n<p><strong>Mati\u00e8re(s) d&rsquo;origine<\/strong><\/p>\n<ul>\n<li>Racine (Winston et Maimes 2007)<\/li>\n<li>Racine et rhizome (EMA 2012)<\/li>\n<\/ul>\n<p><strong>Voie(s) d&rsquo;administration<\/strong><\/p>\n<p style=\"padding-left: 30px;\">Orale<\/p>\n<p><strong>Forme(s) posologique(s)<\/strong><\/p>\n<ul>\n<li>Les formes posologiques pharmaceutiques acceptables comprennent, notamment les bandelettes, les capsules, les comprim\u00e9s, les formes posologiques \u00e0 croquer (p. ex. les comprim\u00e9s, les g\u00e9lifi\u00e9es), les liquides ou les poudres.<\/li>\n<li>Les aliments ou les formes posologiques semblables aux aliments telles que les barres, les gommes \u00e0 m\u00e2cher ou les breuvages, sont exclus de cette monographie.<\/li>\n<\/ul>\n<p><strong>Usage(s) ou fin(s) recommand\u00e9s<\/strong><\/p>\n<p>\u00c9nonc\u00e9(s) pr\u00e9cisant ce qui suit<\/p>\n<ul>\n<li>(Utilis\u00e9 en phytoth\u00e9rapie\/herboristerie) (\u00e0 titre d&rsquo;adaptog\u00e8ne) (pour) aide(r) temporairement au soulagement des sympt\u00f4mes de stress (tels que la fatigue intellectuelle et la sensation de faiblesse) (EMA 2012; Olsson et al. 2009; Winston and Maimes 2007; Pizzorno and Murray 2006; Hoffman 2003)<\/li>\n<li>(Utilis\u00e9 en phytoth\u00e9rapie\/herboristerie pour) aide(r) au maintien des fonctions cognitives (telles que la concentration et la vigueur intellectuelle) (Olsson et al. 2009; Winston and Maimes 2007).<\/li>\n<li>Fournit des antioxydants (Skarpanska-Stejnborn et al. 2009; Winston and Maimes 2007; Kim et al. 2006).<\/li>\n<\/ul>\n<p><strong>Dose(s)<\/strong><\/p>\n<p><strong>Sous-population(s)<\/strong><\/p>\n<p>Adultes (\u2265 18 ans)(EMA 2012)<\/p>\n<p><strong>Quantit\u00e9(s)<\/strong><\/p>\n<p><em>Sympt\u00f4mes de stress et fonctions cognitives<\/em><\/p>\n<p>Extrait normalis\u00e9:<br \/>\nDe 144 \u00e0 680 mg d&rsquo;extrait de rhodiole par jour, sans d\u00e9passer 200 mg par dose unique (EMA 2012; Darbinyan et al. 2007; Pizzorno et Murray 2006)<\/p>\n<p>Activit\u00e9:<\/p>\n<ul>\n<li>0,8-3 % de salidroside (Olsson et al. 2009; AU TGA 2008; Winston et Maimes 2007; Pizzorno et Murray 2006; Brown et al. 2002).<\/li>\n<li>1-6 % de rosavine (Olsson et al. 2009; AU TGA 2008; Winston et Maimes 2007; Pizzorno et Murray 2006; Brown et al. 2002).<\/li>\n<\/ul>\n<p>Teinture:<br \/>\n1,2-1,8 g de racine\/rhizome s\u00e9ch\u00e9(e), par jour (1:4; 4,8-7,2 ml) (Winston et Maimes 2007)<\/p>\n<p><em>Sympt\u00f4mes de stress<\/em><\/p>\n<p>Extrait sec non normalis\u00e9:<br \/>\n144 \u00e0 400 mg d&rsquo;extrait sec, par jour, sans d\u00e9passer 200 mg par dose unique [1.5-5:1, 67-70% d&rsquo;\u00e9thanol v\/v] (EMEA 2012)<\/p>\n<p><em>Antioxidant<\/em><\/p>\n<p><u>Extrait normalis\u00e9:<\/u><br \/>\nJusqu&rsquo;\u00e0 600 mg d&rsquo;extrait de rhodiole par jour, sans d\u00e9passer 200 mg par dose unique (EMA 2012; Pizzorno et Murray 2006).<\/p>\n<p>Activit\u00e9:<\/p>\n<ul>\n<li>0,8-3 % de salidroside (Olsson et al. 2009; AU TGA 2008; Winston et Maimes 2007; Pizzorno et Murray 2006; Brown et al. 2002).<\/li>\n<li>1-6 % de rosavine (Olsson et al. 2009; AU TGA 2008; Winston et Maimes 2007; Pizzorno et Murray 2006; Brown et al. 2002).<\/li>\n<\/ul>\n<p>Extrait sec non normalis\u00e9:<br \/>\n144 \u00e0 400 mg d&rsquo;extrait sec, par jour, sans d\u00e9passer 200 mg par dose unique [1.5-5:1, 67-70% d&rsquo;\u00e9thanol v\/v] (EMEA 2012)<\/p>\n<p>Teinture:<br \/>\nJusqu&rsquo;\u00e0 1,8 g de rhizome\/racine s\u00e9ch\u00e9(e), par jour (1:4; jusqu&rsquo;\u00e0 7,2 ml) (Winston et Maimes 2007)<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Mode(s) d&#8217;emploi<\/strong><\/p>\n<p>Ne pas prendre imm\u00e9diatement avant le coucher (Iovieno et al. 2011; Pizzorno et Murray 2006; Kelly 2001).<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Dur\u00e9e(s) d&rsquo;utilisation<\/strong><\/p>\n<p>\u00c9nonc\u00e9 non requis.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Mention(s) de risque<\/strong><\/p>\n<p>\u00c9nonc\u00e9(s) pr\u00e9cisant ce qui suit<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Pr\u00e9caution(s) et mise(s) en garde<\/strong><\/p>\n<ul>\n<li>Si les sympt\u00f4mes persistent ou s&rsquo;aggravent, consulter un praticien de soins de sant\u00e9.<\/li>\n<li>Si vous \u00eates enceinte ou si vous allaitez, consulter un praticien de soins de sant\u00e9 (EMA 2012).<\/li>\n<li>Si vous prenez un antid\u00e9presseur, consulter un praticien de soins de sant\u00e9 (Iovieno et al. 2011; Olsson et al. 2009; Brown et al. 2002).<\/li>\n<li>Si vous suivez une hormonoth\u00e9rapie de remplacement ou si vous prenez des contraceptifs oraux, consulter un praticien de soins de sant\u00e9 avant d&rsquo;en faire usage (SC 2013; Brown et al. 2002).<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>Contre-indications(s)<\/strong><\/p>\n<p>Ne pas utiliser si vous souffrez de trouble bipolaire ou de trouble du spectre bipolaire (Iovieno et al. 2011; Winston et Maimes 2007; Brown et al. 2002).<\/p>\n<p>&nbsp;<\/p>\n<p><strong>R\u00e9action(s) ind\u00e9sirable(s) connue(s)<\/strong><\/p>\n<p>Si vous souffrez d&rsquo;irritabilit\u00e9 ou d&rsquo;insomnie, cesser de prendre le produit (Pizzorno et Murray 2006; Kelly 2001).<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Ingr\u00e9dients non m\u00e9dicinaux<\/strong><\/p>\n<p>Doivent \u00eatre choisis parmi ceux des (BDIPSN) de la\u00a0DPSNSO\u00a0et respecter les restrictions mentionn\u00e9es dans cette base de donn\u00e9es.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Conditions d&rsquo;entreposage<\/strong>\u00a0la version actuelle de la base de donn\u00e9es d&rsquo;ingr\u00e9dients de produits de sant\u00e9 naturels<\/p>\n<p>\u00c9nonc\u00e9 non requis.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Sp\u00e9cifications<\/strong><\/p>\n<ul>\n<li style=\"text-align: justify;\">Les sp\u00e9cifications du produit fini doivent \u00eatre \u00e9tablies conform\u00e9ment aux exigences d\u00e9crites dans le guide de r\u00e9f\u00e9rence sur la qualit\u00e9 des produits de sant\u00e9 naturels\u00a0de la\u00a0DPSNSO.<\/li>\n<li style=\"text-align: justify;\">L&rsquo;ingr\u00e9dient m\u00e9dicinal doit \u00eatre conforme aux exigences mentionn\u00e9es dans la base de donn\u00e9es d&rsquo;ingr\u00e9dients de produits de sant\u00e9 naturels BDIPSN<\/li>\n<li style=\"text-align: justify;\">Brown RP, Gerbarg PL, Ramazanov Z.\u00a0<em>Rhodiola rosea<\/em>: A Phytomedicinal Overview. HerbalGram 2002;56:40-52.<\/li>\n<\/ul>\n<ul>\n<li style=\"text-align: justify;\">Darbinyan V, Aslanyan G, Amroyan E, Gabrielyan E, Malmstrom C, Panossian A. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Nordic journal of psychiatry 2007;61(5):343-348.<\/li>\n<li style=\"text-align: justify;\">Iovieno, N., Dalton, ED., Fava, M., Mischoulon, D. Second-tier natural antidepressants: review and critique. Journal of Affective Disorders 2011; 130(3): 343-357<\/li>\n<li style=\"text-align: justify;\">Kelly GS.\u00a0<em>Rhodiola rosea<\/em>: A Possible Plant Adaptogen. Alternative Medicine Review 2001; 6(3): 293-302<\/li>\n<li style=\"text-align: justify;\">Kim SH, Hyun SH, Choung SY. Antioxidant effects of Cinnamomi cassiae and\u00a0<em>Rhodiola rosea<\/em>\u00a0extracts in liver of diabetic mice. Biofactors 2006;26(3): 209-219<\/li>\n<li style=\"text-align: justify;\">McGuffin M, Kartesz JT, Leung AY, Tucker AO, editors. Herbs of Commerce. 2<sup>nd<\/sup>\u00a0edition. Silver Spring (MD): American Herbal Products Association; 2000.<\/li>\n<li style=\"text-align: justify;\">Passeportsant\u00e9 2011: Rhodiole<a href=\"http:\/\/www.passeportsante.net\/fr\/Solutions\/PlantesSupplements\/Fiche.aspx?doc=rhodiole_ps\">.<\/a>\u00a0Montr\u00e9al (QC): Totalm\u00e9dia inc.; 2011. [Consult\u00e9 le 12 avril 2013].<\/li>\n<li style=\"text-align: justify;\">Pizzorno JE, Murray MT, editors. Textbook of Natural Medicine. Third edition, volume 1. St. Louis (MI): Churchill Livingstone Elsevier; 2006.<\/li>\n<li style=\"text-align: justify;\">e (MD).\u00a0[<em>Arnica montana<\/em>\u00a0L. Mis \u00e0 jour le 29 mai 2007; Consult\u00e9 le 12 avril 2013].<\/li>\n<li style=\"text-align: justify;\">Winston D, Maimes S. Adaptogens: Herbs for Strength, Stamina, and Stress Relief. Rochester (VT): Healing Arts Press, 2007.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>R\u00e9f\u00e9rences consult\u00e9es<\/strong><\/p>\n<ul>\n<li style=\"text-align: justify;\">Abidov M, Grachev S, Seifulla RD, Ziegenfuss TN. Extract of\u00a0<em>Rhodiola rosea<\/em>\u00a0radix reduces the level of C-reactive protein and creatinine kinase in the blood. Bulletin of Experimental Biology and Medicine 2004;138:63-64.<\/li>\n<li style=\"text-align: justify;\">Blomkvist J, Taube A, Larhammar D. Perspective on roseroot (<em>Rhodiola rosea<\/em>) studies. Planta Medica 2009;75:1187-1190.<\/li>\n<li style=\"text-align: justify;\">Brinker F. Herb Contraindications and Drug Interactions, 3<sup>rd<\/sup>\u00a0edition. Sandy (OR): Eclectic Medical Publications; 2001.<\/li>\n<li style=\"text-align: justify;\">Bystritsky A, Kerwin L, Feusner JD. A pilot study of\u00a0<em>Rhodiola rosea<\/em>\u00a0(Rhodax\u00ae) for Generalized Anxiety Disorder (GAD). The Journal of Alternative and Complementary Medicine 2008;14:175-180.<\/li>\n<li style=\"text-align: justify;\">Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H.\u00a0<em>Rhodiola rosea<\/em>\u00a0in stress induced fatigue &#8211; a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine 2000;7:365-371.<\/li>\n<li style=\"text-align: justify;\">De Bock K, Eijnde BO, Ramaekers M, Hespel P. Acute\u00a0<em>Rhodiola Rosea<\/em>\u00a0Intake Can Improve Endurance Exercise Performance. International Journal of Sport Nutrition and Exercise Metabolism 2004;14:298-307.<\/li>\n<li style=\"text-align: justify;\">Edward D, Heufelder A, Zimmermann Z. Therapeutic Effects and Safety of\u00a0<em>Rhodiola rosea<\/em>\u00a0Extract WS\u00ae 1375 in Subjects with Life-stress Symptoms &#8211; Results of an Open-label Study. Phytotherapy Research 2012;26:1220-1225.<\/li>\n<li style=\"text-align: justify;\">Hung SK, Perry R, Ernst E. The effectiveness and efficacy of\u00a0<em>Rhodiola rosea<\/em>\u00a0L: A systematic review of randomized clinical trials. Phytomedicine 2011;18:235-244.<\/li>\n<li style=\"text-align: justify;\">Ishaque S, Shamseer L, Bukutu C, Vohra S.\u00a0<em>Rhodiola rosea<\/em>\u00a0for physical and mental fatigue: a systematic review. Complementary &amp; Alternative Medicine 2012;12:70-78.<\/li>\n<li style=\"text-align: justify;\">Noreen EE, Buckley JG, Lewis SL, Brandauer J, Stuempfle KJ. The effects of an acute dose of\u00a0<em>Rhodiola rosea<\/em>\u00a0on endurance exercise performance. Journal of Strength and Conditioning Association 2013;27(3):839-847.<\/li>\n<li style=\"text-align: justify;\">Panossian A, Wilkman G, Sarris J. Rosenroot (<em>Rhodiola rosea<\/em>): Traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine 2010;17:481-493.<\/li>\n<li style=\"text-align: justify;\">Parisi A, Tranchita E. Duranti G, Ciminelli E, Quaranta I, Ceci R, Cerulli C, Borrione P, Sabatini S. Effects of chronic\u00a0<em>Rhodiola rosea<\/em>\u00a0supplementation on sport performance and antioxidant capacity in trained male : preliminary results. The Journal of Sports Medicine and Physical Fitness 2010;50:57-63.<\/li>\n<li style=\"text-align: justify;\">Peschel W, Prieto JM, Karkour C, Williamson EM. Effect of provenance, plant part and processing on extract profiles from cultivated European\u00a0<em>Rhodiola rosea<\/em>\u00a0L. for medicinal use. Phytochemistry 2013;86:92-102.<\/li>\n<li style=\"text-align: justify;\">Shevtsov VA, Zholus BI, Shervarly VI, Vol&rsquo;skij VB, Korovin YP, Khristich MP, Roslyakova NA, Wikman G. A randomized trial of two different doses of a SHR-5\u00a0<em>Rhodiola rosea<\/em>\u00a0extract versus placebo and control of capacity for mental work. Phytomedicine 2003;10:95-105.<\/li>\n<li style=\"text-align: justify;\">Skarpanska-Stejnborn A, Pilaczynska-Szczesniak L, Basta P, Deskur-Smielecka E. The influence of supplementation with\u00a0<em>Rhodiola rosea<\/em>\u00a0L. extract on selected redox parameters in professional rowers. International Journal of Sport Nutrition and Exercise Metabolism 2009; 19(2): 186-199<\/li>\n<li style=\"text-align: justify;\">Spasov AA, Wikman GK, Mandrikow VB, Mironova IA, Neumoin VV. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of\u00a0<em>Rhodiola rosea<\/em>\u00a0SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine 2000;7:85-89.<\/li>\n<li style=\"text-align: justify;\">Walker TB, Altobelli SA, Caprihan A, Robergs RA. Failure of\u00a0<em>Rhodiola rosea<\/em>\u00a0to alter skeletan muscle phosphate kinetics in trained men. Metabolism 2007:56(8):1111-1117.<\/li>\n<\/ul>\n<p><strong>\u00a0<\/strong><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>SOURCE- SANT\u00c9 CANADA\u00a0: Nomenclature du compendium des ingr\u00e9dients m\u00e9dicinaux M\u00e9dicaments et produits de sant\u00e9 naturels Monographie: Rhodiola roseola La pr\u00e9sente<\/p>\n","protected":false},"author":1,"featured_media":5757,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"colormag_page_container_layout":"default_layout","colormag_page_sidebar_layout":"default_layout","footnotes":""},"categories":[821,891],"tags":[],"class_list":["post-5245","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-divers-articles-blogue-phytonutriment-canada","category-plantes-medicinales"],"_links":{"self":[{"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/posts\/5245","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/comments?post=5245"}],"version-history":[{"count":1,"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/posts\/5245\/revisions"}],"predecessor-version":[{"id":10421,"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/posts\/5245\/revisions\/10421"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/media\/5757"}],"wp:attachment":[{"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/media?parent=5245"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/categories?post=5245"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.phytonutriment.ca\/fr\/wp-json\/wp\/v2\/tags?post=5245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}